Moxibustion can be done after 3:00 pm. According to the theory of the five elements of yin and yang, some scholars believe that the effect of moxibustion is better in the morning than in the afternoon, but some studies have found that in some diseases treated with moxibustion, the hour of needling has no significant effect on the efficacy, and some patients even have better efficacy in the afternoon. In fact, moxibustion is usually the best in the morning, but it is not significantly less effective in the afternoon. Moxibustion is a warming stimulus for the treatment of related diseases, which can help Yang, open the meridians, and dispel cold, and is suitable for many kinds of deficiency-cold evidence, and is also beneficial for some real-heat evidence. Factors that significantly affect the efficacy of moxibustion include the severity of the patient’s disease, the course of moxibustion and the accuracy of the doctor’s operation, which need to be adjusted by the doctor according to the patient’s specific situation. In addition, moxibustion is not recommended in the morning or afternoon in humid and rainy weather, as the pores of the body are open during moxibustion, and moxibustion at this time can easily cause moisture in the air to enter the body, which will not only affect the effect of moxibustion, but may also aggravate the symptoms. Although the effect of moxibustion in the morning or afternoon is not significantly different, but need to pay attention to avoid night moxibustion, the body’s Yang Qi has been in a resting state at night, the defense is weaker, moxibustion at this time the body can not resist external evil, easy to aggravate the symptoms. When moxibustion, we need to pay attention to the state of the body and the moxibustion site, too hungry, too full, extreme fatigue are not recommended for moxibustion. The face, joints and tendons are not suitable for scar moxibustion, and women should be careful not to overdo it during pregnancy.