A needle wound contaminated with blood or body fluids from an AIDS patient needs to be treated promptly. First, the local wound needs to be rinsed repeatedly with soap and running water, and then the local area should be disinfected with alcohol or iodophor. For the local wound can squeeze out the blood, need to repeatedly squeeze, can minimize the chance of occupational exposure. Oral blocking medication is needed within 24 hours, and it is generally recommended to be taken within 4 hours, the earlier the better. The general course of oral medication is 28 days, and attention needs to be paid to monitoring HIV antibodies after oral medication is taken.