Cancer pain, or advanced cancer pain, is one of the main causes of suffering for patients with advanced cancer. At this stage, patients are in considerable physical and mental pain, and a significant number of patients die not directly from cancer, but from severe pain. About 80% of advanced cancer patients have severe pain, and it is estimated that at least 15 million people in the world experience pain every day. Cancer pain has been recognized as a painful disease. However, some cancer patients still have severe pain after strict application of the “three-step drug treatment plan”, or they are unable to accept the treatment of the “three-step plan” because they cannot eat, have contraindications to drugs, cannot tolerate the side effects of analgesics, or have too much financial burden to take drugs, etc. They are called persistent cancer pain or refractory cancer pain. Refractory cancer pain is an indication for nerve destruction block. Thoracoscopic visceral neurotomy is an effective pain relief method, which has been proven by foreign scholars. Thoracoscopic visceral neurectomy provides an excellent way to control chronic cancer pain. It is a less invasive, safer and more effective treatment for intractable severe pain caused by liver, gallbladder, pancreas and other upper abdominal organs, and is a more ideal pain relief treatment method worth promoting. Thoracoscopic visceral neurectomy provides an excellent way to control chronic cancer pain. We have successfully applied thoracoscopic visceral neurectomy to relieve the pain of more than ten cases of various advanced cancer pain in upper abdomen!