Atypical hyperplasia refers to the abnormal proliferation of cells. There is no exact time to develop to cancer, and the development time is not fixed according to individual conditions, so it cannot be generalized. Clinically, atypical hyperplasia is often classified into 3 levels according to the degree of abnormal hyperplasia. Grade I is mild atypical hyperplasia, grade II is moderate atypical hyperplasia, and grade III is severe atypical hyperplasia. In case of rapid progress, moderate atypical hyperplasia may develop into cancer within 1-3 years, and severe atypical hyperplasia may develop into cancer within 1 year. 1. Grade I atypical hyperplasia: Grade I atypical hyperplasia is mostly inflammatory reactions, which are benign and usually do not develop into cancer, often occur in the gastrointestinal tract, uterine mucosa and breast hyperplasia, and require regular follow-up. Problems such as hyperplasia and polyps can be treated surgically and can return to normal after eliminating the cause. During the treatment period, it is necessary to exercise properly to enhance physical fitness, avoid spicy and stimulating food, avoid smoking and alcohol, eat more vitamin-rich food, pay attention to balanced nutrition, and maintain good sleep and mentality; 2. Grade II atypical hyperplasia: Grade II atypical hyperplasia is a kind of precancerous lesion, which has the possibility of further malignant transformation. If no intervention is taken, it may develop into cancer in 1-3 years. It is necessary to check the location and nature of lesions in regular hospitals and take appropriate treatment according to the doctor’s recommendation, including surgery and conservative treatment. Conservative treatment requires regular follow-up and review to detect the development process of lesions, and timely surgery is required if cancerous lesions appear; 3. Grade III atypical hyperplasia: Grade III atypical hyperplasia needs to be distinguished from carcinoma in situ, which generally evolves from grade I and grade II atypical hyperplasia that cannot be controlled and may become cancerous within about one year. It is difficult to reverse the development of hyperplasia at this stage, and the probability of turning into cancer is high, so active treatment is needed, such as physical therapy, laser treatment, cryotherapy, and surgical excision. For atypical hyperplasia, early detection and early treatment is the key to cure the disease. Patients need to actively cooperate with doctors to avoid further development into invasive cancer.