The third dose of New Coronavirus recombinant vaccine is usually required within 6 months after the first dose. People who delayed the vaccination for various reasons should also have a catch-up vaccination as soon as possible. The vaccination does not guarantee 100% efficiency, so self-protection and proper wearing of masks are also needed during the daily period to reduce the infection rate of New Coronavirus. The vaccine is an antigenic component that works by regulating the immune system and stimulating antibody production. The vaccine that requires three doses is mainly a recombinant protein vaccine, the main component of which is a recombinantly constructed antigenic protein, basically without the involvement of the virus, and has a high safety level. After the injection of the recombinant vaccine, antibody production takes longer and is slower than that of the inactivated vaccine and recombinant vaccine. Therefore, the entire vaccination procedure needs to be completed in three doses, with an interval of more than 4 weeks between two adjacent doses, and the three doses need to be completed within 6 months as much as possible to ensure that the neo-coronavirus vaccine works better to prevent neo-coronavirus infection and the occurrence of severe disease. Even for those who have not completed the vaccination within the prescribed time, it is generally not necessary to start a new vaccination program, and it is sufficient to go to the vaccination site as early as possible to get the corresponding doses.