Hyperthyroidism does not usually cause urticaria. The onset of urticaria usually can not find the exact cause, usually associated with the ingestion of certain foods, infections, drugs and other causes, various causes lead to mast cell activation and degranulation, the release of inflammatory mediators, resulting in increased vascular permeability leading to limited edema, i.e. urticaria. Hyperthyroidism patients usually do not appear urticaria manifestations, hyperthyroidism common clinical manifestations of irritability, excessive sweating, irritability, panic, fatigue, weight loss, hyperphagia, diarrhea, protruding eyes, etc., may also cause anterior tibial mucous edema, thyroid crisis, thyrotoxic heart disease and other complications. Therefore, when hyperthyroidism patients appear urticaria symptoms should be timely consultation, under the guidance of the doctor for standardized treatment, early treatment and early promotion of patient recovery.