Is individualized treatment the best solution?

TheCancerCentre, where oncologist Dr. Wong works, is located in the Paragon Shopping Center, and this is one of the advertisements he saw when he walked by the mall one day. He said, “Most people choose ready-made products and buy them after trying them on. Only some demanding customers will consider tailor-made clothing, after all, according to the figure of custom-made clothing, must be more fit and good-looking.” Genes are the blueprint for tumor metabolism, he said, and so is cancer treatment. It’s more effective for patients to receive a “tailored” treatment plan than an even-size therapy. It’s not about looking good or not, it’s a matter of life and death, and must be handled more carefully. He emphasized that “tailor-made” cancer treatment is more important than tailor-made clothing. Dr. Huang further explained, “Very often, the same type of cancer may look the same in X-ray photos and the same in biopsy under the microscope, but cancer tumors and genes are different, and the structure of deoxyribonucleic acid (DNA) is also different, and genes are the blueprint for tumor metabolism, determining how resistant it is to drugs or which drugs it responds to. The genes are the blueprint for tumor metabolism, determining how resistant they are to drugs or which drugs they respond to, etc. Patients with similar cancer tumors cannot be treated the same way by doctors, but must be treated differently from person to person, and personalized treatment is the best approach.” Not long ago, a female lung cancer patient came to Dr. Huang for treatment, and he gave her a personalized treatment. The patient asked him, “How do you know this treatment is right for me?” Dr. Huang answered the patient because he had performed cellular tests on her and knew that she had a mutation in her cell genes and that there was a growth switch on the surface of the cancer cells, and that if he could block it with targeted drugs to keep it from sending signals, the cancer cells would slowly die. After looking at the patient’s genetic tests, we were at least 70 to 80 percent confident,” he said. Two months after this patient received tailored treatment, the tumor was completely under control.” Dr. Wong also cited the example of another lung cancer patient, saying, “This patient came to me saying that a friend of his had come to me with excellent results in treating his cancer and wanted to use the same treatment in hopes of curing his condition. We extracted this patient’s cells and the lab results found no mutation in this type of cell gene that would make him unfit to receive the same treatment as his friend. However, he thought it was the latest targeted therapy, so why not for him!” In the end, this patient could only use the traditional treatment method and undergo conventional chemotherapy, which also successfully controlled the tumor. Dr. Wong compared oncologists to tailors, who must know how to customize the most suitable clothing for their clients. The doctor must consider whether the patient has other diseases such as diabetes, heart disease, hypertension, age, drug mix and dosage, and how to minimize side effects with other drugs in order to develop a successful treatment.