Acute urticaria is usually due to infection, allergy and other factors that cause patients to develop symptoms such as erythema, windsock, etc. In severe cases, respiratory difficulties and laryngeal edema may be manifested, and should be treated immediately in an emergency room. When the symptoms are mild, medication can be chosen, and those with severe symptoms need to be treated with epinephrine injection and opening the airway. 1. Pharmacological treatment: for mild symptoms such as erythema and clamminess, oral cetirizine, loratadine, benadryl and other drugs can be used for anti-allergy treatment, and oral prednisone can be used to relieve acute phase reactions if necessary. 2. First aid treatment: patients in the acute attack will appear shortness of breath, respiratory spasm, laryngeal edema and other phenomena, the need to immediately take the head high and feet low position, will be biased to the side, clean up the oral cavity of foreign objects, and oxygen therapy, if the symptoms are not relieved, if necessary, to take the injection of epinephrine, tracheotomy, cricothyroid perforation and other ways to keep breathing unobstructed. Acute urticaria acute attack has a certain risk of asphyxiation, it is recommended to seek medical attention in a timely manner, under the guidance of a physician reasonable treatment, drugs need to be used in accordance with the doctor’s instructions, do not self-medication.