Age-related macular degeneration is prevalent in people over 50 years of age, with the incidence increasing with age, and is categorized as dry or wet. The clinical hallmark of the dry form is the vitreous wart, a deposit of subretinal pigment epithelium between the retinal pigment epithelium basement membrane and Bruch’s membrane. Large vitreous warts are a risk factor for progressive development of AMD and vision loss, with fluorescent contrast of early hypofluorescence and late hyperfluorescence. Vitreous warts combined with subretinal fluid, hemorrhage, or lipid exudates caused by choroidal neovascularization are characteristic of exudative AMD. Supplementation with micronutrients and antioxidants may be effective.