The doctrine of functional localization of the nervous system holds that a specific part of the brain governs a specific function, and damage to that part means that a specific functional disorder occurs. Previously, under the influence of the theory of non-regenerative brain cells, brain infarction was considered irrecoverable once it occurred, thus creating a situation in which neurology emphasized diagnosis over treatment, believing that no more effective treatments were available. However, basic research as well as clinical practice now prove that it is possible or conditional to recover function after cerebral infarction. The current understanding of brain plasticity has gradually evolved from denial and controversy to basic agreement. Brain plasticity has not been studied much, and there are very few studies on the effects of acupuncture. Brain plasticity refers to the ability of brain tissue to repair itself structurally and functionally [1] and is an important basis for clinical treatment [2]. We observed dynamic changes in a series of indicators marking the degree of ischemic damage, axonal dendritic repair, synaptic plasticity and neural regeneration after cerebral ischemic injury, aiming to study the material basis and mechanisms of brain plasticity after cerebral infarction and its relationship with behavior, and observed the effects of acupuncture and applied them to clinical treatment. In clinical practice, we have combined the theory of brain plasticity with the theory of neurorehabilitation, and developed the theory and technique of acupuncture to promote the passage of the brain, i.e., the acupuncture should not only be combined with the meridian theory, but also pay attention to the changes of muscle tone – this essential difference and neuromuscular anatomy, and applied it to clinical practice, and observed the therapeutic effect.