Foci of intrahepatic calcification can encase necrotic or damaged tissue and promote its recovery, so factors that cause liver damage can cause foci of intrahepatic calcification.
Disease factors: e.g. hepatitis, liver tuberculosis, liver abscess, liver encapsulation, liver schistosomiasis, liver cancer, liver haemangioma, liver metastatic tumours, etc.
Medication factors: frequent use of oral contraceptives, or use of estrogen and progestin, immunosuppressants and other drugs to treat disease.
Environmental factors: living in infected water areas or frequent close contact with people suffering from infectious diseases of the liver.
Dietary factors: lack of dietary hygiene, consumption of mouldy food, preference for greasy and high-fat food, etc.
Personal factors: congenital dysplasia, disorders of calcium and phosphorus metabolism, smoking, alcoholism, etc.