Hemorrhagic fever and nephrotic syndrome is a natural epidemic disease caused by a virus, with the mouse as the main source of infection, with three major features and five phases of typical performance. The fever is accompanied by three pains, i.e. headache, lumbago, orbital pain and three rednesses, i.e. congestion and flushing of the skin of the face, neck and anterior chest. 2. hypotensive shock period, mainly plasma loss hypovolemic shock, the longer the hypotensive shock, the more serious the damage to renal function. 3. oliguric period, the urine volume is less than 400mL per day showing acute renal failure. 4. polyuric period, the urine volume exceeds 2000mL in 24 hours, which is the sign of entering polyuric period, sometimes the urine volume reaches 5.Recovery period, urine volume decreases back to 2000mL per day, symptoms gradually disappear, urinary routine and biochemical abnormal changes return to normal, 90% of the basic recovery within two months.