The presence of a sore throat and cough with yellow sputum indicates a bacterial infection in the throat. In the case of bacterial infection, an inflammatory reaction occurs in the throat, which is accompanied by redness, swelling, heat, and pain, so the throat feels sore. In addition, the throat will secrete inflammatory substances and neutrophils in the body will gather in the throat to swallow foreign bacteria, and these neutrophils will then undergo lysis and necrosis, resulting in yellow sputum. At this time, it is often necessary to take antibiotics for treatment, such as cefixime, cefradine, cefalexin or amoxicillin. If there are allergies to these drugs, they can be replaced with azithromycin or roxithromycin for treatment. It is also necessary to take phlegm-transforming drugs. For the transformation of yellow phlegm, the more effective ones are aminoglutethimide oral solution and pulmonary cough combination, and the more recommended one is pulmonary cough combination.