The difference between rheumatoid arthritis and gout lies in the different etiology, clinical features and laboratory test results, as follows: 1. Different etiology: The etiology of rheumatoid arthritis is still unclear and may be related to genetics, infection, environment and other factors, while the cause of gout is mainly hyperuricemia. 2. The main reason for this is that it is a very important factor in the development of the disease. Both are inflammatory joint diseases, both will appear elevated blood sedimentation, C-reactive protein and other inflammatory indicators.