What is necrotizing fasciitis?

  Acute necrotizing fasciitis is an acute necrotizing infection caused by bacterial invasion of the subcutaneous tissue and fascia. 1952 Wilson named this progressive necrosis of the subcutaneous tissue fascia as acute necrotizing fasciitis. The disease initially resembles a general tissue infection, but progresses rapidly with rapid involvement of subcutaneous tissues and deep fascia, causing tissue circulation disorders due to swelling at the lesion site, giving the lesion area a characteristic purplish-red color of the skin, and as the disease continues to progress, subcutaneous tissue and fascial necrosis gradually appears and involves skin necrosis outwardly. The cause of this disease is not clear, but the inflammatory reaction and toxin absorption can lead to systemic toxicity, which is characterized by sepsis.  The onset of severe infection such as perineal necrotizing fasciitis is rapid and progresses rapidly, and these patients are often accompanied by wasting diseases, and their systemic or local defenses are already reduced, so if they are not treated early and correctly, the sepsis mortality rate can be 34%-73%. Local manifestations are acute, progressive, necrotizing infections involving mainly the skin and subcutaneous fascial tissues. It is characterized by a change in skin color, surrounded by a submerged skin margin, and may be associated with pain. Early local examination shows localized edematous depressions on palpation, with marked fluctuating sensation and limited or widespread twisting pronunciation. Systemic manifestations: systemic toxic symptoms are obvious, chills and hyperthermia. Leukocytes are significantly elevated, hypoxemia, hypoproteinemia, etc.