I. Indications The first step after diagnosis is to correct hypoxemia and metabolic acidosis, etc. As soon as the child is diagnosed after birth, prostaglandins should be given intravenously to bring down the pulmonary artery pressure and keep the arterial duct open. In severe cyanosis, balloon atrial septal stoma should be performed to reduce the symptoms of hypoxia. Anatomic correction (switch procedure) should be performed within two weeks. In cases of combined ductus arteriosus or ventricular septal defect, concurrent correction can be performed around 6 months after birth. Patients may also be considered for switch surgery within 2 months after birth, but pulmonary artery pressure should be measured. If the pressure in the left ventricle and pulmonary artery decreases, circumferential reduction (Banding) of the pulmonary artery should be performed first along with a shunt from the unnamed artery to the right pulmonary artery to train the left ventricular function. Surgery should be performed as soon as possible within 1 to 2 weeks after annuloplasty; delay in surgery increases the risk. Surgical treatment 1. Palliative treatment Balloon atrial septoplasty (Rashkind procedure): If the hypoxia is severe and radical surgery cannot be performed, balloon atrial septoplasty or atrial defect enlargement is feasible to make a large amount of blood mixing at the atrial level and improve the arterial oxygen saturation so that the child survives until it is suitable for radical surgery. Pulmonary artery annuloplasty: In complete transposition of the great arteries with large ventricular septal defect, pulmonary artery annuloplasty can be performed within 6 months to prevent pulmonary vascular lesions caused by congestive heart failure and pulmonary hypertension. 2, radical surgery (1) physiological correction (Senning or Mustard surgery): can be performed within 1 to 12 months after birth, that is, the use of autologous pericardium and atrial wall in the atrium to build a plate barrier, the body circulation of venous blood directed to the mitral valve and into the left ventricle, and the pulmonary vein bleeding back to the tricuspid valve and into the right ventricle, the formation of atrioventricular connection inconsistency and ventricular macrovascular connection inconsistency. To achieve physiological correction. (2) Anatomic correction surgery (switch surgery): can be performed within 4 weeks after birth, i.e. aortic and pulmonary artery interchange and coronary artery re-grafting to achieve complete correction of the anatomic relationship. The surgical conditions are: left/right ventricular pressure ratio >0.85, left ventricular ejection fraction >0.45, left ventricular end-diastolic volume >90% of normal, left ventricular posterior wall thickness >4-4.5mm, and ventricular wall tension <12000 dyne/cm2. III. Surgical results In the 1980s, intra-atrial diversion was mainly used to treat transposition of the great arteries, and in recent years, there is a tendency to do anatomical correction ( switch surgery). In the early stage, the mortality rate of this operation was high, but in recent years it has been reduced to 0-4.2%, and the efficacy is very good. Long-term follow-up found that the children with TGA who underwent switch surgery were physiologically and psychologically no different from the normal population, and the children with poor recovery after surgery were slightly worse than normal people.