Epithelioid trophoblastic tumors can be misdiagnosed. Epithelioid trophoblastic tumors originate from chorioallantoic intermediate trophoblasts and are a unique and rare type of trophoblastic tumor. Epithelioid trophoblastic tumors can be misinterpreted due to the histologic features of both trophoblastic tumors and carcinomas, which can easily make pathologic diagnosis difficult. Those with epithelioid trophoblastic tumors are usually seen in women in their reproductive years and tend to present with irregular vaginal bleeding, but during pelvic examination, a mass in the uterine area can be found. The diagnostic criteria for epithelioid trophoblastic tumors is mostly diagnostic curettage. It is recommended that patients considering epithelioid trophoblastic tumors should go to regular hospitals for consultation and clear diagnosis.