For patients in whom preoperative evaluation allows localization of the epileptogenic focus and surgical treatment, intraoperative cortical EEG (ECoG) can further identify the epileptogenic focus, guide the extent of surgical resection, and assess the completeness of resection. However, in fact, we rarely use (ECoG) to localize the seizure initiation area. Because the intraoperative (ECoG) detection time is short, the meaning is unclear, and the interference by anesthesia and other factors is high, it is difficult to record the washout EEG during the seizure phase except for a few patients. Intraoperative electrical cortical stimulation can be used for intraoperative localization of functional brain areas, in addition to inducing discharges, clinical subencephalic seizures, aura seizures and clinical seizures, and thus for auxiliary localization of intraoperative epileptogenic foci. Intraoperative electrical cortical stimulation can induce both habitual and non-habitual seizures. The significance of intraoperative electrical stimulation for localizing epileptogenic foci is still highly controversial. The distribution of intraoperative interictal spikes, the onset and duration of post-discharge, and the local brain tissue stimulation to induce the patient’s usual seizures are not always used to accurately localize the area of the epileptogenic focus. Stimulation intensity, stimulation pulse width, stimulation frequency, stimulation duration, and stimulation fraction may affect the outcome of electrical stimulation. Therefore, when intraoperative electrical stimulation is performed to locate the epileptogenic focus, various factors need to be taken into account to carefully analyze and locate the epileptogenic focus.