Hyperthyroidism is an abbreviation for hyperthyroidism. It is a condition in which the thyroid gland synthesizes and releases too much thyroid hormone, resulting in hyper-metabolism and sympathetic excitation, causing palpitations, sweating, increased eating and bowel movements, and weight loss. Most patients also often have proptosis, eyelid edema, and vision loss. In severe cases, hyperthyroidism may lead to critical phase, coma or even life-threatening. 1. Talkative and hyperactive, mental and nervous system hypersensitivity, lack of concentration, restlessness and irritability, nervousness and anxiety, restlessness and insomnia, memory loss. Sometimes there are hallucinations, and even manifest as sub-mania or schizophrenia. Occasionally, it manifests as oligophrenic depression and apathy. There may also be reaching, eyelid, tongue extension fine tremor, etc. 2. Hypermetabolic syndrome: Patients often have (1) fear of heat and sweating, warm and moist skin, which may be accompanied by hypothermia. In case of crisis, there may be high fever. (2) fatigue and weakness, easy to hunger, more food and wasting. (3) Ocular manifestations: upward vision without forehead wrinkling, downward vision with lids falling late; proptosis, less transient eyes, wide fissure and difficult to gather. Benign proptosis has no sensation, while malignant proptosis has many symptoms. (Malignant proptosis is also known as infiltrative proptosis, endocrine proptosis, etc. The degree of proptosis is more than 18 mm, there may be extraocular muscle paralysis, periorbital edema, etc. Patients often complain of photophobia, lacrimation, eye pain and stinging pain.) 4. The digestive system often includes hyperphagia, hyperphagia and emaciation. Older patients with hyperthyroidism may have loss of appetite and anorexia. Diarrhea is often present. 5. The cardiovascular system may have palpitations, shortness of breath and chest tightness. Heart rate increases, and in severe cases, there is atrial fibrillation, heart enlargement and heart failure. Systolic blood pressure is increased, diastolic blood pressure is decreased, and pulse pressure is increased. Most of the goiter is diffusely and symmetrically enlarged. The degree of enlargement is not obviously related to the severity of hyperthyroidism and can move up and down with swallowing movements. There is tremor on palpation and vascular murmur on hearing. 7. Musculoskeletal system Most patients have muscle weakness and muscle atrophy. Chronic myopathy is mainly proximal muscle weakness and atrophy, male patients may be accompanied by periodic paralysis. 8, reproductive system women often have reduced menstruation or amenorrhea, men have impotence, occasionally male breast development, etc.. 9, Other patients may have mild anemia, the elderly and children often have atypical performance.