If urticaria is not cured for a long time, then it can develop into chronic urticaria, or accompanied by symptoms of the digestive tract, respiratory system and other symptoms. Urticaria is a common skin disease, the cause is very complex, may be related to allergies, infections, autoimmune and other factors, easy to recur. 1. Chronic urticaria: If urticaria remains untreated, it is likely to gradually turn into chronic urticaria. Not only does the frequency of attacks increase, but also the rash or itching symptoms may be more severe. 2. Induce digestive symptoms: the patient’s digestive system may be affected, which in turn triggers a series of uncomfortable symptoms, such as nausea, vomiting, abdominal pain, diarrhea and so on. 3. Impact on the respiratory system: the respiratory system of some patients will be affected to a certain extent, resulting in laryngeal edema, dyspnea, chest tightness and shortness of breath, etc., and in serious cases, it may even be life-threatening. It is recommended that patients go to the hospital for standardized diagnosis and treatment in a timely manner, and follow the doctor’s instructions for regular use of medication.