Itching when the body is hot is usually seen in patients with urticaria, which has the potential to heal on its own. The itchy body when it is hot may be caused by allergy-induced hives, such as eating allergy-prone foods or inhaling allergic pollen or dust, if it occurs within a short period of time. Once the patient is removed from the allergic environment, the symptoms will gradually subside. In addition, the itchy body can also be seen in cholinergic urticaria, mainly due to exercise, heat, nervousness, eating hot drinks or alcoholic beverages, etc., so that the cholinergic nerve impulses and release acetylcholine, the action of the mast cells to release itching inflammatory irritation factors. Patients mainly present with a round papule-like rash on the skin, which may be surrounded by a red halo and accompanied by intense itching, tingling or burning sensation, and the symptoms may resolve on their own when the body temperature drops. However, if the symptoms are more severe, oral antihistamine or anticholinergic medication can also be used, as well as topical application of glyburide lotion to clear heat and relieve itching. In addition, patients should avoid sweating a lot in their daily life, keep their body cool, avoid heat, mental tension, eating hot drinks or alcoholic beverages, etc. to reduce the onset of urticaria.