Parkinson’s disease is a degenerative disease of the nervous system characterized by manifestations of resting tremor, bradykinesia, myotonia, and postural gait disturbances. In recent years, it has been increasingly noted that non-motor symptoms such as depression, constipation and sleep disturbances are also common discomfort manifestations in patients with Parkinson’s disease, and their impact on patients’ quality of life even exceeds that of Parkinson’s disease motor symptoms. Most Parkinson’s patients have sleep disorders such as insomnia, sleep fragmentation, and changes in sleep behavior. The mechanisms by which sleep disorders occur may be related to alterations in transmitters and damage to central structures. The presence of movement disorders in Parkinson’s disease itself can also produce various sleep problems, such as tremor, myotonia, and oculomotor spasms, all of which can interfere with sleep and increase the number of awakenings in patients, leading to sleep fragmentation. In addition, drugs commonly used to treat Parkinson’s disease, such as dopamine agonists and anticholinergic agents, can also cause sleep disruption in some patients with Parkinson’s disease. Parkinson’s disease-related sleep disorders The most common manifestations are difficulty falling asleep and difficulty maintaining sleep. Sound production during sleep and daytime sleepiness are also common. The incidence of sleep disorders increases as the disease progresses in Parkinson’s patients. The degree of sleep disturbance is also exacerbated by depression and dementia that occur after Parkinson’s disease. Short-term trials of alprazolam, zolpidem, chloral hydrate, and olanzapine are available for Parkinson’s disease patients with sleep disorders. Drugs such as amitriptyline or trazodone hydrochloride may be considered to control the condition if accompanied by depression.