There are various factors that cause sleep disorders in patients with Parkinson’s disease, partly related to the disease itself or its symptoms, but also related to the patient’s age, other complications, and medication. Possible etiological factors are as follows: 1, the influence of age-related aging factors Normal elderly people with increasing age, sleep structure changes, that is, the non-rapid eye movement sleep of the 3, 4 stages of sleep is reduced, usually shortened night sleep, there are a number of times during the day a small sleep, sleep is easily disturbed, about 40% of the healthy elderly people complain of chronic insomnia. These are related to a variety of factors such as sleep apnea, nocturnal enuresis and nocturnal myoclonus in the elderly, but there are significant differences in the form and severity of sleep disorders in elderly patients with Parkinson’s disease, therefore, age is not the only factor in sleep disorders in Parkinson’s disease. 2, the disease itself on the sleep center structure and transmitter The loss of nigrostriatal dopaminergic neurons in Parkinson’s disease leads to transmitter imbalance in the brain, which is the biochemical basis for sleep disorders. For example, the degeneration of dopaminergic neurons in the limbic system of the midbrain is related to the upward reticular activating system, and the degeneration of the pathway originates from the dorsal nucleus of the middle suture and the nucleus of the blueprint, which impairs the arousal system and can promote the occurrence of sleep disorders, thus affecting daytime arousal and causing excessive sleep. 3, the impact of nocturnal movement disorders Nocturnal movement disorders are more common in patients with Parkinson’s disease, especially in the late stage. As the disease progresses, nocturnal motor symptoms such as early morning dystonia, nocturnal freezing, inability to sit still, restlessness and tremor are gradually severe. Periodic limb dyskinesia and RBD and other sleep movement disorders can lead to insomnia in patients with PD. In addition, problems such as nocturia and “off” phase-related incontinence and spasticity occur more frequently and also disrupt sleep. 4, the impact of anti-Parkinson’s disease drugs The main anti-Parkinson’s disease drugs have the effect of changing the sleep habits of patients with Parkinson’s disease, such as a variety of dopaminergic agents have a dual role in sleep, small doses can improve sleep, large doses can lead to insomnia or sleep disorders induced to the dopamine agonist is more common, a study suggests that the dopaminergic agent affects the sleep patterns of light and medium-sized patients, the heavy patients through the improvement of their nocturnal dyskinesias to improve sleep quality, and that either long-term or high-dose applications worsen sleep disorders.