Drug interaction refers to the drug interactions that may occur if the drug is used together with other drugs, such as reduced efficacy, enhanced efficacy, aggravated adverse reactions and other related contents. For example, sodium phenobarbital is a liver enzyme inducer, which can increase the blood concentration of certain drugs. If these two types of drugs must be used at the same time, the dosage of the latter should be appropriately reduced to avoid poisoning caused by high blood concentration. For this kind of special cases, doctors must have special account. Cao Wenlan, Department of Oncology, Xiyuan Hospital, Chinese Academy of Traditional Chinese Medicine, drug overdose may cause adverse symptoms to most patients after overdose, or special discomfort caused by a few patients. In most cases, it can be relieved by stopping the drug immediately and then taking supportive or symptomatic treatment according to the symptoms, and if the drug is overdosed within a short period of time and the patient has no contraindication, the method of inducing vomiting or gastric lavage can be taken. Storage refers to the optimal environment for storing medicines, such as humidity and temperature. A suitable storage environment can maximize the quality and efficacy of the drug during its shelf life, such as many biological preparations, which should be stored in the refrigerator’s freezer. The above is a summary of the considerations for our national drug instructions. In the U.S., drug instructions can be read by everyone, and they are designed for the patient’s benefit, reflecting the patient’s care: the instructions should list the foods and drugs that cannot be taken together with the drug and the activities that are not suitable for the patient; what to do if the patient forgets to take the drug or takes one less dose; how to store the drug is also explained. In Japan, since 2004, illustrations have been included in drug instructions to make it easier for patients of different cultural levels to read and understand. Many foreigners in Japan and foreign tourists visiting Japan buy medicines at local pharmacies, and if medicines are not used properly, it may lead to unnecessary accidents, and with the use of manga illustrations, even if you do not speak the language, you can still understand the usage of medicines in general, thus reducing medication errors. In 2005, the European Union introduced a model instruction manual for patients: the instruction manual is divided into six parts according to the procedures of patients’ use: what the drug is, what to pay attention to before using the drug, how to use it, possible adverse reactions after using the drug, how to store it and other information. In the “before medication” section, contraindications, the relationship between medication and food, and the effects of medication on driving are mentioned. In the “How to use”, in addition to the dosage, it is also important to explain what to do after an overdose, what to do if you miss a dose, and what to do when you stop taking the medication, which are all common problems encountered by ordinary patients in taking medication, and these contents are rarely reflected in some of the drug instructions in China. In the “possible adverse reactions”, instead of medical terminology, some symptoms are described so that patients can judge for themselves, such as jaundice, which is described as yellowing of the skin of the eyes, telling patients to seek medical attention when they experience yellowing of the skin of the eyes. According to this model, the UK has been well received by doctors and patients since July 2005 when the original kind of lengthy instructions were abolished and patient-specific instructions were adopted, and fewer accidents caused by medication errors were found, which are what we should learn and improve. In short, the body is our own, before using medication, we also need to take some time to carefully read the important content of the drug instructions related to you, to guide us to use medication healthily.