If the uterorectal fossa effusion is caused by physiological factors, generally no treatment is needed. If it is caused by pelvic inflammatory disease, endometriosis, etc., it should be treated with drugs and surgery. 1. Physiological factors: if a small amount of menstrual blood reflux during menstruation can occur in the uterorectal fossa effusion, may also be due to peritoneal secretion, can be self-absorbed, without special treatment. 2. Pelvic inflammatory disease: it is a common infectious disease of female upper genitalia, which may be caused by pathogen infection. Patients may have the phenomenon of uterorectal fossa fluid accumulation, which can be treated with oral cephalosporin, levofloxacin and other drugs. 3. Endometriosis: Most common in women of childbearing age, may appear the phenomenon of uterorectal fossa fluid. Non-steroidal anti-inflammatory drugs such as indomethacin, ibuprofen, etc., progesterone such as megestrol and other medications can be used for treatment, for patients who are not effective in drug treatment, surgical treatment is feasible. Uterorectal fossa fluid exclude physiological factors, we should go to the hospital in time to identify the cause of the disease to take symptomatic treatment, to avoid delaying the condition.