There are many causes of sciatica, common causes include trauma, local compression, lesions of the nerve itself, etc. According to the different causes, corresponding treatments should be taken. 1. Trauma: Acute sprain, fall and flutter injuries and other causes, resulting in injury to the sciatic nerve, may cause different degrees of neuropathy, thus inducing sciatic nerve pain. 2. Local compression: common lumbar disc herniation, lumbar spinal stenosis, etc., compression of local nerves, resulting in radiating pain, if the buttock pyriformis syndrome, will also compress and stimulate the nerve, nerve pain symptoms. 3. The lesion of the nerve itself: clinically common peripheral neuritis, diabetic neuropathy, etc., may also produce sciatica, the need for active treatment of the underlying disease, for patients with peripheral neuritis, comply with the doctor’s instructions for anti-inflammatory such as gabapentin, carbamazepine and other drug therapy. For patients with diabetes, treatment with hypoglycemic drugs such as metformin and dagliflozin under the guidance of a medical professional can alleviate the symptoms. Sciatica may be related to a variety of factors, it is recommended to visit the hospital in time for early treatment to avoid aggravation of the condition.