Axillary sweat glands are categorized into eccrine sweat glands (also known as eccrine sweat glands because of their small size) and parietal sweat glands (also known as eccrine sweat glands because of their large size). In recent years, another type of sweat gland (the third type of sweat gland in the armpit) has been discovered, with a morphology between the two, but its function is still unclear. Exocrine sweat glands are located in the dermis, mainly by the cholinergic nerve secretion of acetylcholine transmitter innervation, secretion of a large number of water-based, sodium, potassium and other ions in the sweat, the regulation of body temperature and the body’s water, electrolyte metabolism. If it is hyperfunctional and secretes too much sweat, it is called “hyperhidrosis”. Top secretion sweat glands are mainly located in the superficial subcutaneous layer, adjacent to the dermis, which in addition to cholinergic nerve innervation, but also by other adrenergic nerve innervation, the main secretion of some unsaturated or hydroxylated branched-chain fatty acids, secretion to the surface of the skin by the bacterial decomposition of the material can produce a special smell, thus affecting people’s lives. If it is hyperfunctional and secretes too much material with special odor, it is called “armpit odor disorder”. Botulinum toxin A is a neurotoxin that acts by specifically blocking the release of acetylcholine from cholinergic nerve endings. Clinical treatments are safe doses, widely used, such as “facial biological wrinkle”, “bite muscle injection face”, “gastrocnemius muscle injection calf thinning” and so on. Now it has been applied to the treatment of “armpit odor” and “hyperhidrosis”, and is considered to be a reliable, non-invasive and worth promoting new methods. Botulinum toxin is very effective in inhibiting nerve cells from secreting the neurotransmitter acetylcholine, so it can inhibit the excitability of the sympathetic nerves that control the sweat glands and promote the secretion of sweat by the sweat glands. The secretion of sweat from our body’s sweat glands is also controlled by the sympathetic nerves through the use of acetylcholine as a transducer. Many patients do not sweat when they are sleeping, resting, relaxing, or when the sympathetic nerves are not excited. They sweat when they exercise or when they are nervous (sympathetic excitation). Therefore, local injection of botulinum toxin in the armpits can achieve a very good antiperspirant effect, and the odor of the armpits will also be removed because the bacteria will no longer decompose and produce odor after no sweating. Generally there is no unsuitable people, unless the toxin protein allergy, so it is best to observe the injection rest 10-20 minutes before leaving the hospital The earliest some patients with hyperhidrosis of the hands using ganglionic cauterization method, the range is large and not easy to control, resulting in compensatory sweating will be very serious and extensive. Botox has now taken the place of this procedure. The use of Botox in the treatment of hand sweating focuses on the sweaty palms of the hands, where compensatory sweating is rare. If Botox is used in patients with axillary hyperhidrosis or armpit odor, the chance of compensatory sweating is even lower. Generally speaking, the effect of treating hand sweating, armpit odor, and axillary hyperhidrosis can be seen 3-7 days after the injection of Botox, and the effect can last for 4-6 months. If the person is suffering from this problem in summer, it is enough to administer the medicine once a year, and if the person is suffering from this problem for the whole year, he/she may need to be injected twice. If the next N years are playing this drug, from the current experience of Botox injections to thin the face biological wrinkle removal surgery is still very safe. This is because these cosmetic patients are also injected every six months some patients have been injecting for many years. Generally as long as it is not a small dose of short intervals of injection, generally will not produce drug resistance. Sweat glands exist in many parts of the human body, in addition to the bilateral armpits of the sweat glands are more concentrated, more, in the perineum around the anus around the umbilicus around the nipple areola area may have a small number of sweat glands exist. After armpit surgery or Botox injections, the secretion of sweat glands in other parts of the body should be unaffected. So it is possible that some odor may still remain in the private parts of the body. However, the degree will definitely be greatly reduced compared to that before the treatment. Moreover, the parts are usually more hidden, so if personal hygiene is taken care of, it will not have a great impact on daily life and work.