The most common and direct clinical symptom manifestation of rheumatoid arthritis is pain in the joints; the physical pain caused by rheumatoid arthritis to patients is also pain in the joints. In addition to causing pain in the joints, rheumatoid arthritis also causes swelling, stiffness, unfavorable flexion and extension, ankylosis and deformity of the joints, all of which seriously affect the daily activities of rheumatoid patients. Therefore, when we receive treatment, the first claim to efficacy is pain relief, improvement of joint function, and restoration of normal mobility. In rheumatoid treatment, hormonal drugs are the first to provide “immediate” pain relief, while certain biological agents developed in recent years can also provide significant pain relief and restore normal joint function in a relatively short period of time. We should not blindly reject the rational treatment by specialists, including the correct use of hormones; illegal doctors’ “homemade drugs” often illegally add hormones to obtain “miraculous” curative effects, so that patients have confidence and dependence on his drugs, and he can continue to “earn money”. Non-steroidal anti-inflammatory and analgesic drugs, also have a relatively good anti-inflammatory and analgesic effect, can be very good to improve the clinical symptoms of rheumatoid patients, so in the treatment of rheumatoid, combined drug use program, there are such drugs. This is what we usually call “symptomatic” drugs, rheumatoid arthritis treatment, is required to treat both the symptoms and the root cause, improve the pain symptoms of the joints, is the most typical “symptomatic” treatment. However, if the “symptoms” are not properly treated, it is easy to affect the patient’s trust in the doctor and the treatment. However, this is not the only “hard truth” in the treatment and rehabilitation of rheumatoid arthritis. There are two other issues that may be more important, but are sometimes overlooked: interruption of the disease process and monitoring of side effects. Rheumatoid arthritis has its own unique pathological process, and eliminating clinical symptoms such as joint pain does not mean that rheumatoid is well controlled or well treated; to examine the treatment of rheumatoid, we must also look at one more “hard truth”: the blocking of the progression of rheumatoid disease. Rheumatoid arthritis is the greatest danger to the human body, with its damage to the bone, which is a slow development of a pathological process under the premise that rheumatoid arthritis is not well controlled, is a progressive process – continuous development, more and more serious, and even irreversible. This pathological development is potentially masked by the presence of painkilling drugs. In the treatment of rheumatoid arthritis, mere “no pain” does not mean that bone destruction is suppressed; “no pain” is accompanied by the likely presence of inflammation, and as long as inflammation exists, there may be a pathological process that destroys bone. The inflammation of rheumatoid arthritis is caused by immune dysfunction, and the treatment of inflammation must be accompanied by the correction of immune problems, which is the use of immunosuppressive agents. Pharmacological studies have proven that effective immunosuppressive therapy has the function of slowing down bone destruction, so immunosuppressive drugs are called “disease-modifying” drugs. This is a class of drugs in the sense of “cure”. The most direct evidence of the efficacy of immunosuppressive drugs is the decrease in immune indicators related to rheumatoid disease; indirectly, the inflammation is controlled, and the joints remain relatively normal without the use of hormones and non-steroidal anti-inflammatory drugs, and no significant pain is felt. At the same time, the X-rays show the stability of the bone. Because of the reality of drug side effects, side effect monitoring must be given a high priority in treatment. Curing the disease but eating the liver and kidneys is not the purpose of rheumatoid treatment either. Safe control of toxic side effects, is also the rheumatoid treatment “hard truth”. Some people think that the side effects of Western drugs, afraid to use, is unnecessary. A western drug in the market before, are subject to strict toxic side effects research and clinical observation, the use of dose determination, there is a scientific basis, as long as the drug is used under the guidance of a specialist, formal monitoring, generally will not cause serious side effects. Many problems in the use of drugs have a lot to do with the irregular use of drugs, self-medication and negligent examination of patients. The ideal rheumatoid treatment effect is safe and effective, but the reality is not so “ideal”, rheumatoid treatment, there are often a variety of problems, part of the individual differences in patients, part of the medical environment, we need to have a correct understanding of this, do not blindly the disease treatment effect is not ideal The rheumatoid disease is a difficult disease, difficult to treat”, “undead cancer” and so on.