Positive high-risk HPV indicates that the organism is infected with high-risk HPV, which may cause cervical cancer. However, whether the specific positive high-risk HPV is serious or not, it needs to be combined with the type of infection, clinical manifestations, examination results and time of infection for comprehensive judgment, and patients are suggested to actively seek medical treatment: 1. High-risk type: If the result shows that the type of infection is positive for HPV6 and HPV11, at this time The situation is lighter and it is easier to control the development of the disease. If the results show that the type of infection is HPV16, HPV18 positive, it suggests a high-risk infection, the situation is more serious; 2, clinical manifestations: if the clinical manifestations only appear genital parts of the condyloma acuminata or cervical intraepithelial lesions of low degree, generally the situation is not serious. If it affects the female cervix, there is a possibility of malignant lesions causing cervical cancer, the situation is more serious; 3, test results: when TCT examination is carried out, if the test results are normal, observation can be carried out first, which is not serious at this time, after 3 months of observation, re-examination, if the results are still positive, and TCT examination suggests cervical intraepithelial neoplasia, the situation is more serious at this time, timely treatment should be carried out to control the development of the disease 4, the time of infection: for young women, there may be a transient infection, if their own physical fitness, most of them can self-clear the virus, the condition is not serious at this time, the re-examination results can be turned negative. If the patient is positive for high-risk HPV for a long period of time, the condition may be more serious and it is recommended to follow the medical advice for antiviral treatment to reduce the risk of cervical cancer. Patients can undergo cervical biopsy and tumor marker tests to rule out the possibility of cervical cancer, and then take oral and topical antiviral drugs under the guidance of a doctor, including common drugs such as interferon, acyclovir, and cidofovir. If patients have cervical cancer, they are advised to take surgery, radiotherapy, chemotherapy and other treatments to control the disease after the tumor stage is clearly defined. In addition, patients are advised to maintain a good attitude, face the positive indicators correctly, cooperate with doctors for active treatment, keep the perineum clean and avoid unclean sexual life on a daily basis.