Breast cancer is a highly heterogeneous disease and not all patients receive the same surgical approach and post-operative adjuvant treatment, so individualized treatment plans can be developed to allow patients to receive the most appropriate treatment and avoid unnecessary over-treatment to improve quality of life. Individualized treatment: 1. Individualized surgery: According to the patient’s preoperative examination, imaging and other means, we can design the surgical plan of breast preservation, nipple preservation or radical surgery. 2, individualization of chemotherapy: the most reliable for clinical use is pathological analysis, conclusive and correct pathological type and molecular pathological analysis is an important basis for determining the postoperative chemotherapy regimen. Some patients do not need chemotherapy, or very strong chemotherapy. 3. Individualization of endocrine therapy: Estrogen receptor (ER) and progesterone receptor (PR) testing can guide whether or not endocrine therapy is feasible, and either one of them is positive. Combined with the ki67 and HER2 tests, endocrine sensitivity can be analyzed, and this information can be fed back to the physician to adjust the appropriate chemotherapy regimen. Some patients with very safe breast cancer who have undergone radical surgery can also be treated without endocrine therapy. The medication is different for patients before and after menopause. 4. Individualization of radiotherapy: Pathological results and surgical methods are important bases for deciding radiotherapy. Individualization is reflected in the need for radiotherapy and the site of radiotherapy. Radiotherapy does not benefit every patient. Certain underlying diseases suggest that patients should not receive excessive radiotherapy.