Amyotrophic lateral bundle sclerosis is the most common type of motor neuron disease, selectively damaging the anterior horn of the spinal cord and the motor nerve nuclei of the brainstem, and most patients die after about 1-2 years due to respiratory paralysis or co-infections of the lungs, with a very poor prognosis. Western medicine currently has no effective treatment to alleviate the disease process, and only some symptomatic and supportive measures can be taken. Traditional Chinese medicine believes that this disease belongs to the category of impotence L. The common patterns include lung-heat and fluid injury, damp-heat encroachment, spleen-stomach deficiency, liver-kidney deficiency, and heart-kidney deficiency, and most of them are treated by internal herbal medicine for diagnosis and treatment. However, the efficacy of traditional Chinese medicine is still unsatisfactory as reported in the limited literature. The author used internal Chinese medicine, supplemented with medicinal diets, together with acupuncture and auricular acupoints to treat this disease, and achieved significant results. Liu x x, female, 48 years old, came to the clinic in October 2008 because of “weakness of limbs with muscle atrophy and slurred speech for more than half a year”. The patient was physically fit in the past, but in February 2008, muscle weakness in the right hand began to occur slowly without any obvious cause, gradually developing into both hands and arms and both lower limbs, and she was unsteady in standing and needed help from others, gradually developing into distal muscle atrophy of the limbs, and she had difficulty in speaking with slurred speech. In April 2008, she was diagnosed with motor neuron disease amyotrophic lateral bundle sclerosis in a local hospital. After being given vitamin drugs, improve brain tissue metabolism and other drugs, the effect is not good, and then in a Chinese medicine hospital using Chinese medicine, acupuncture, small knife and other treatments, the effect is still not good, the disease progressive development, so in August 2003 to seek treatment in Diao Benzhu director. At the initial diagnosis, the symptoms were: limb impotence and weakness, needing family support to walk slowly, speech effort, slurred speech, dizziness, insomnia and dreaminess, sometimes feeling phlegm in the throat, difficult to cluck out, fatigue and laziness, impatience and irritability, sometimes depression and easy to cry, thirst and no desire to drink, yellowish color, red tongue, yellowish greasy moss, fine string pulse. The syndrome was characterized by internal phlegm-heat and deficiency of essence in the liver and kidney. Treatment adopts the method of driving away the evil and supporting the positive, driving away dampness and eliminating phlegm, and at the same time benefiting qi and nourishing essence. In the first dose, the formula was: 30g of Herba Euphrasia, 3g of Radix Bupleurum, 10g of Pericarpium Citri Reticulatae, 3g of Rhizoma Bamboo Roots, 12g of Rhizoma Bupleurum, 15g of Rhizoma Pinelliae, 15g of Rhizoma Pinelliae, 15g of Rhizoma Pinelliae, 30g of Rhizoma Cimicifuga, 30g of Salviae, 30g of Jujubae Seed, 30g of Rhizoma Ophiopogonis, 10g of Rhizoma Ophiopogonis, 10g of Fructus schisandrae and 30g of Red Codonopsis. The patient felt less dizziness and insomnia, but the pharynx was still sticky with phlegm, making it difficult to swallow, and the limbs were weak and impotent, with a red tongue, yellowish moss and a thin pulse. This qi essence is slightly restored, and then feel the external evil, treatment is given to the pharynx and lungs, increase the strength of clearing heat and phlegm. The formula was: 10g of Saganum, 15g of Xuanhu, 10g of Ma Jong, 10g of Platycodonopsis, 15g of Tangerine root, 15g of Corydalis, 15g of Hypericum, 15g of Donghua, 15g of Yinhua, 30g of Plum blossom, 10g of Haihai, 30g of Su Zi, 30g of White mustard, 30g of Leptosphaeriae, 30g of Polygala, 10g of Acorus calamus, 3g of Acupuncture: Baihui, Fengchi, Fengfu, Daxi, Leiqiu, Heggu, Yinlingquan, Fenglong; Moxibustion: Tiantu, lungs, 18 (18) cracked woven grass. After 4 doses of dysentery (15) cough, the patient reported a clear throat, no more dizziness, insomnia, but still felt limb weakness and difficulty in speaking, with a red tongue, yellowish and slightly greasy, and a fine pulse. Liver and kidney essence deficiency was recognized. Treats tonifies essence, disperses wind and facilitates orifices and clears internal heat. Huang Lian 3g Jiao Gardenia 3g Yuan Zhi 3g Calamus 3g Yi Zhi Ren 30g Tian Ma 15g Crocus sativus 30g Tortoise Plate 10g Turtle Ace 10g Sour Zao Zao Ren 30g Salvia miltiorrhiza 30g Qiang Wu 3g Angelica dahurica 3g Ligusticum chuanxiong 3g Ligusticum ziziphi 3g Hosoctonia serrata 3g Dietary supplements: Yuan Zhi 3g Calamus 3g Tian Ma 15g Yiduoyun 30g Sour Zao Zao Ren 30g Steamed Pig Brain Flower 1payment, remove the dregs and drink the broth two times a day. Acupuncture: Baihui, Si Shencong, Shenmen, Anmian, Liejiao, Hegu; musk moxibustion: Zhiyang, Anguoji, Foot Sanli, Sanyinjiao, Yongquan; auricular acupuncture: Brain Point, Shenmen, Liver, Kidney. After taking 6 consecutive doses, the patient felt that his limbs were obviously strong, walking smoothly, even walking backwards at will, speaking easily, pronouncing clearly, and in a happy mood, which made him look like a different person compared with that of 3 months ago. Later on, on the basis of the prescription, with the addition and subtraction of symptoms, together with acupuncture and medicinal dietary treatment, the patient’s condition has been stable so far, and has not relapsed. The patient’s condition has been stable so far, with no recurrence. Western medicine has no effective drugs, the use of Chinese medicine integrated therapy treatment, achieved significant results, although this is a case, but for this kind of difficult diseases, still has an important guiding value. My experience is that for difficult diseases, on the basis of accurate diagnosis, the joint use of a variety of effective therapeutic measures can increase the efficacy of treatment, which is precisely the advantages of Chinese medicine internal and external treatment. 1.Accurate diagnosis, clear treatment rules, and appropriate choice of medicine: this patient is a middle-aged woman with half yin; living in the wetland for a long time, dampness and heat are generated within the body, which becomes poisonous over a long period of time and depletes the yin of the liver and kidney; her temperament is impatient and irritable, which leads to the loss of liver detachment and excretion, poor qi, and the depression and transformation of fire, which on the one hand burns Jin into phlegm and on the other hand injures the yin essence; the superimposition of multiple causes accelerates the depletion of yin essence in the liver and kidney. The diagnosis belongs to the internalization of phlegm-heat and deficiency of essence of the liver and kidney. This is a case of deficiency of the root and symptoms of the symptoms of the disease. The treatment should be to support the correctness and dispel the evil, but most of the medicines that replenish essence are nourishing and greasy and hinder the evil, therefore, the symptoms should be treated first to dispel the phlegm-heat, and then to support the correctness and replenish the essence. Selection of medicines should be carefully considered. Since ancient times, many doctors blindly follow the “wind and impotence mixed with” the paralysis, the use of insect medicine. In this case, the patient did not use insect medicine from beginning to end, because the insect medicine has the effect of resting the wind to stop spasm, in the impotence of the L disease mechanism does not match. Closely around the mechanism of drug selection and not blindly follow the paralysis is also the key to achieve good results in this case. 2, the skillful use of medicinal diets: medicinal diets are effective, convenient and practical, easy to adhere to for a long time. In this case, we adopted the medicines of farzhi, calamus, tianma, a cloud, sour jujube kernel, etc. to steam the pig brain flower, to fill the real essence with blood, flesh and sentient products, and all the medicines played the effect of nourishing the spirit and waking up the brain, cleansing the phlegm and opening up the orifices. 3. Needling and moxibustion were coordinated. This patient used to acupuncture diarrhea Baihui, four Shencong, musk moxibustion warm Yongquan-based acupuncture methods, known as “diarrhea south and fill the north” and a flexible application, and Chinese medicine, medicinal diet together with the expulsion of phlegm and heat, replenish essence, nourish the spirit to wake up the brain, dredge the meridians and channels, regulate the qi and blood, so that the muscle muscle and bones Rongrun, limb movement of the role of freedom. The author believes that the treatment of amyotrophic lateral bundle sclerosis with Chinese medicine is a promising method that is worth further exploration.