At present, there is no effective treatment for this disease, and the main treatments are as follows.
1. Riluzole may delay the onset of respiratory dysfunction and prolong survival in ALS patients by reducing glutamate release in the central nervous system and attenuating excitotoxic effects, but it cannot improve motor function and muscle strength. It is suitable for patients with please, moderate disease, but it is more expensive, and the adult dose is 50 mg orally, 2 times/d. Side effects include weakness, nausea, weight loss and increased transaminases.
2.Vitamin E may be beneficial for ALS patients, and many patients are treated empirically with vitamin E. Various trials of nerve growth factor therapy are underway, and experimental and clinical studies of stem cell therapy for ALS are in the exploratory stage.
3.Symptomatic treatment such as salivation can be given to anticholinergic drugs such as scopolamine, atropine and antan; myospasm can be given to valium, chlorambucil, clozarazone, etc.; pulmonary infection should be actively prevented, brace or bracing can improve the patient’s motor ability, passive exercise and physical therapy can prevent limb contracture.
4, supportive therapy is quite important to ensure adequate nutrition and improve the general condition of patients, severe swallowing difficulties need to be given a semi-liquid diet, through the gastric tube nasal feeding or percutaneous gastrostomy to maintain normal nutrition and water intake, when patients have respiratory distress, respiratory support can prolong the life of patients, home can be used to relieve hypercapnia and hypoxemia in patients with mild symptoms through oral or nasal positive pressure ventilation, advanced severe respiratory distress Patients need to rely on tracheotomy to maintain ventilation. The newly invented breathing device that can produce artificial cough is very beneficial to patients and can effectively help them clear their airways and prevent aspiration pneumonia from occurring.
Chinese medicine treatment for amyotrophic lateral sclerosis.
The TCM approach to the treatment of amyotrophic lateral sclerosis is actually two major dialectical therapies, as follows.
1, dry heat injury.
Treatment: nourish Yin, nourish blood, moisten dryness and produce fluid.
Prescription: clear dryness soup. Clear the dryness and save the lung soup plus reduction. If the dryness and heat are more severe, add Huang Bai and Yin Hua to clear the heat and dryness; if the muscle bundle trembles, add Antelope horn and Hooked vine to calm the liver and quench the wind.
2. Liver and kidney yin deficiency.
Treatment: Nourish Yin, soften tendons, and nourish Liver and Kidney.
Remedies: Add or subtract muscle and marrow soup, or Tiger Qian Wan, Dihuang Drink. If the limbs are numb and weak, add tianma and gui zhi to pass Yang and soften tendons; if the limbs tremble significantly, add antelope horn. If the limbs are dry and dry, add Dendrobium, chasteberry to nourish Yin and moisten dryness; if the palms are hot and red, add Xuan Shen to nourish Yin and clear heat; if Yin deficiency and Yang, add Semen Cuscutae, Cistanches, Huang Jing to nourish both Yin and Yang; if the tongue is atrophied and speech is lame, add White Pithospermum, Scorpion to soothe the meridians and clear the heart, or add Calamus, Yu Jin, Musk to open the orifice and clear the heart.
3, spleen and kidney deficiency.
Treatment: strengthen the spleen and kidneys, and nourish the blood and muscles.
If the muscle is soft and weak, add Gui Zhi, Sheng Ma to pass Yang and warm the meridian; if mental fatigue, reuse Ginseng, Qi to warm the middle and replenish Qi; if the mouth is light and less, add Chinese yam, lentils to strengthen the spleen and open the stomach; if the face is floating and short of breath, add Mai Dong, Wu Wei Zi, Poria to benefit the heart and lungs; if the meat is impotent and thin, add Huang Jing, Fructus Lycii, Shu Di to nourish Yin and glory the muscle; if the bones are atrophied and limbs are soft, add Tiger Bone, Du Zhong If the bone is atrophied and the limbs are weak, add tiger bone and dulcimer; if the impotence and premature ejaculation, add Xian Ling Spleen and Ba Ji Tian to nourish the kidney and strengthen the yang; if the kidney yang is weak and obvious, add Radix et Rhizoma Polygonati and Cinnamon.
The onset of the disease is slow and mostly occurs in the middle and old age, so clinical deficiency is common, the disease involves the liver, spleen and kidney, liver and kidney yin deficiency can be accompanied by internal heat, the spleen and kidney yang deficiency can be accompanied by dampness, blood stasis, but all are the evidence of both, the clinical evidence is less separate type, based on the disease of Chinese medicine clinical symptoms are similar, so there is also a slow chart of the treatment of adult medicine or homemade pills.
4, fumigation method.
5, massage and massage method.
(1) pounding method: need to hold an empty fist with both hands, back and forth to pound both sides, or combined with pounding its corresponding abdomen, 20 times each.
(2) Mo method: first of all, we should use the palms of both hands to rub hot, massage both sides of the waist, 50 times per side, once a day in the morning and evening, one of the traumatic muscle atrophy treatment methods.
(3) push method: press the waist with the root of the palms of both hands, push up and down with force, the action should be fast and strong until it is hot, once a day in the morning and evening. It has the effect of promoting the circulation, moving qi and activating blood.