How does preeclampsia develop? The first trimester of pregnancy is a critical period for the development of the fetal heart structure and cannot be “disturbed” in any way. If during the development of the fetus, due to viral infection, radiation exposure, history of medication, history of diabetes, nutritional disorders, environmental and genetic factors, or if the tissues that should degenerate after birth fail to degenerate, defects in the heart, commonly known as “holes”, such as abnormal connections, dysplasia, atresia, or abnormal channels, may occur, i.e. Congenital heart disease. The most common congenital heart malformations include: ventricular septal defect, atrial septal defect, atrial defect, patent ductus arteriosus, simple pulmonary valve stenosis, tetralogy of Fallot, aortic stenosis and aortic constriction. The seven malformations account for about 3/4 of all precardiac disease. Infants with precardiac disease often exhibit puzzling behaviors such as incessant crying, inexplicable agitation, and difficulty being “soothed. Don’t think of these behaviors as “unintelligent”; they are indicators of possible heart problems. At the same time, these infants rarely feel hungry or even in pain. In addition, these children often have sweating, shortness of breath and a dry cough. Parents should be alert to the following signs of precardiac disease in their children 1. Frequent colds, recurrent bronchitis and pneumonia. 2.Infants have difficulty in feeding or refuse to eat, choking and coughing, often eating and stopping, shortness of breath, pale face, breath-holding, etc. 3.The skin continues to appear cyanosis, which is most obvious at the tip of the nose, lips of the mouth and nail roots of the fingers and toes. 4.Children who can walk often crouch down voluntarily for a moment while walking or playing. 5.Older children have thickened and darkened finger and toe end segments. 6.Easy fatigue, poor physical strength, sweating in general, greening around the mouth, hemoptysis. 7, abnormal development, manifested as thinness, growth retardation, etc. 8.The child develops chest pain and syncope. Precocious heart disease in infancy and early childhood disease progresses rapidly, if the disease can be detected and treated in time, the vast majority of precocious heart disease can be completely cured through surgery, and patients can live and work as normal people after surgery. At present, the success rate of surgical treatment for infantile precocious heart disease is over 90%.