How to treat laryngeal papilloma extending into the subglottis or trachea?

  Patient: Papillary tumor in the trachea, April 08. After laboratory tests and laser cutting, it recurred in about 70 days. I would like to know if there is a better drug to control its growth.  Xu Chengzhi: The trachea is no longer part of the larynx, but the heavier laryngeal papillomas can extend to the subglottis or trachea. I think what you are talking about may belong to this situation, and it is estimated that the pathology is clear that it is a papilloma. It is now believed that papilloma may be related to HPV infection, and the scope of this viral infection is much larger than the actual growth of the tumor. The HPV infection is the root cause of recurrence. Surgery, especially CO2 laser, is the most recognized treatment in China, but pediatric laryngeal papilloma is very prone to recurrence, which may be related to the poor immune tolerance of pediatric patients to the virus, and there are reports of local injection of chemotherapy drug 5-Fu after resection, but it is too damaging to pediatric patients. In addition, postoperative interferon therapy can be applied. There are also reports of the application of opium oil after excision (Chinese medicine has anti-tumor effects, which may not be available in many western hospitals), but personally, I think it is better to remove it by laser, supplemented by liquid nitrogen freezing of the trauma during surgery, and adhere to interferon therapy after surgery.