The criterion for cure is no recurrence after stopping the medication. About two-thirds of patients with chronic urticaria are cured, and the other third have difficulty stopping the medication. Hives that last longer than 6 weeks and more than 2 episodes per day can be diagnosed as chronic urticaria. There are many causes of chronicity, the common ones are: 1. untimely treatment, acute delay into chronicity; 2. allergic constitution, insensitivity to treatment. 3, combined systemic diseases, such as gastritis, cholecystitis, thyroid disease, etc. 4.Continued exposure to allergens. 5, poor lifestyle habits, such as infections, alcohol, penicillin and other triggers. For patients with chronic urticaria, it is recommended that sequential oral anti-allergic drugs, first choose 1-3 anti-allergic drugs, control the rash, so that one does not occur, after the condition is stable, gradually reduce the drug, each time only reduce the partial dose of 1 drug, such as no relapse after the reduction, then to be stable, the body adapted to the new dose, then consider the next step of drug reduction, and finally to achieve the discontinuation of drugs. During the reduction period, if the rash rebound, the previous medication regimen should be resumed. At the same time, you can take Yu Ping Feng granules, anti-wind and anti-itch granules, thymidine enteric capsules, compound glycyrrhizin, etc., staggered to improve the body quality and immunity. If the treatment is prolonged, it is recommended to improve the systematic physical examination and screen for chronic diseases. Chronic urticaria is relatively difficult to treat, but there are many successful precedents, and patience and standardization are the guarantee of cure.