The low pregnancy rate may be due to the woman’s own problems, or may be related to the spouse, both spouses can be examined together to clarify the causes and deal with them: 1. Immune function abnormalities: women with positive anti-sperm antibodies and positive anti-endometrial antibodies are unable to achieve the smooth union of sperm and egg, which will also lead to a low chance of pregnancy; 3, tubal blockage: due to infection, injury, inflammation and other reasons caused by partial or even total blockage of the fallopian tubes, it is difficult for the fertilized egg to reach the uterus after formation, and the chance of successful conception will be reduced or even zero, depending on the situation, tubal 4, uterine development malformation: such as the presence of a longitudinal uterus or stump uterus, the mother can not provide the conditions for conception, will lead to infertility; 5, abnormal frequency of sexual behavior: the frequency of sexual behavior between men and women is too low, or only in the non-ovulatory sex, will reduce the probability of pregnancy; 6, other factors: such as poor dietary habits, alcohol, smoking, mental tension, staying up late, etc. can also lead to difficulties in conception. Second, spousal sperm abnormalities male oligosperm, azoospermia, high sperm malformation rate will lead to difficulties in fertilization and reduce the chances of female pregnancy. To sum up, the reasons for not easy to conceive are more and more complicated, so it is recommended that both men and women conduct a comprehensive physical examination before preparing for pregnancy, and pay attention to strengthening the influence, adjusting work and rest, and quitting bad habits to help improve the probability of conception.