Drugs used to treat chronic pancreatitis include painkillers, pancreatic enzyme preparations, proton pump inhibitors or H₂ receptor antagonists such as pethidine, pancreatic enzyme enteric-coated tablets, omeprazole and famotidine. It is recommended to use them under the guidance of a doctor. Chronic pancreatitis is a common digestive disease, mainly manifested as abdominal pain, diarrhea or steatorrhea, emaciation, jaundice, abdominal mass and diabetes. 1. Painkillers: Painkillers such as pethidine can relieve some of the abdominal pain. 2. Pancreatic enzyme preparations: For patients with abdominal pain, oral pancreatic enzyme preparations can relieve part of the abdominal pain, and pancreatic exocrine insufficiency needs to be treated with high-activity, enteric-coated pancreatic enzyme replacement. Pancreatic enzymes should be taken with meals, and the dosage can be adjusted according to the degree of diarrhea and abdominal distension of the patient. 3. Proton pump inhibitors or H₂ receptor antagonists: inhibit gastric acid secretion, which can reduce the activation of pancreatic enzymes by gastric acid. Omeprazole enteric-coated tablets or famotidine tablets are commonly used. Patients with chronic pancreatitis must abstain from alcohol and smoking, and avoid excessive high-fat and high-protein diets. As it is difficult to cure, and pancreatic endocrine and exocrine insufficiency and pancreatic cancer may occur in those who continue to progress, regular follow-up should be paid attention to.