Subhealth is a new concept proposed by the medical profession in recent years. Subhealth is a state in which the human body is in between health and disease, manifested as symptoms of reduced vitality, function and adaptability within a certain period of time, and often does not meet the clinical or subclinical diagnostic criteria of modern medicine related to diseases, if there are symptoms that cannot be explained in current medicine and last for 3 months or more, it can be judged as subhealth. Subhealth chronic fatigue is a clinical symptom complained by patients. Patients often feel a lack of energy or physical strength, and feel tired and weak, accompanied by dizziness, poor concentration, memory loss, low mood, night sweats, abnormal stools, poor appetite, palpitations, and even if they get enough sleep, they still have difficulty in recovering their energy and physical strength, and their fatigue continues to increase after exercise, etc. These symptoms often last for more than three months to six months. Domestic survey shows that more than 70% of the subhealthy people have fatigue symptoms, and the survey believes that long-term work tension, competitive pressure and other important causes of subhealthy fatigue state. Foreign surveys show that about 24% of the population have fatigue symptoms, of which about 2%-4% have symptoms lasting for more than 6 months. People with medium or higher income and low income are the most common group, and some special groups such as computer software designers, medical workers and people with long-term irregular life are prone to suffer from chronic fatigue. In terms of gender, middle-aged and young women are the majority of patients. Some patients may also suffer from depression and anxiety, but the effect of conventional antidepressant and anxiety treatment is poor. Many clinical diseases can cause fatigue, such as anemia, occult abscess, rheumatic diseases, endocrine diseases, malignant tumors, multiple sclerosis, etc., but most of these diseases can be clearly diagnosed by physical and chemical examinations. There are also some patients who have anxiety, depression, obsessive-compulsive and other psychological disorders despite normal physical and chemical examinations, and these people are also a common group of people with fatigue. The combination of medication and health education can help patients to relieve the pain of fatigue. For how to diagnose and treat subhealth chronic fatigue patients early, the majority of patients should pay attention to the following points: 1, pay attention to a healthy lifestyle, usually live regularly, including study, work, diet, sleep, exercise, etc. 2, correct self-regulation, especially in the face of stressful events in life, to learn to self-reduce stress and maintain a good state of mind. 3.If the fatigue lasts for more than 3 months and cannot be completely relieved by rest, you should go to the hospital promptly. 4.Patients who are not convenient to come to the clinic can first communicate with me through telephone consultation.