If a woman is negative for closed antibodies, she cannot conceive and needs to be treated for positive closed antibodies in order to conceive and have a healthy baby only if she is positive. The length of time it takes for a woman to turn positive with treatment for closed antibody is determined by a combination of factors. It usually depends on the woman’s physical condition and her daily routine. During the treatment period, the time to turn positive varies depending on the nature of the woman’s body. Generally speaking, a course of closed antibody treatment can turn positive in about 2-3 months, but there are some people who have poor absorption capacity when doing closed antibody treatment, resulting in no turn positive at the end of the course of treatment. In this case, it is necessary to continue with the closed antibody injection until the positive result is achieved. In addition to physical differences, irregularities in a woman’s daily life can also lead to a lapse of time after treatment with closed antibody. Women who stay up late at night and who are under a lot of stress may have poor absorption of the medication, which may lead to a slower effect of the medication and prolong the time to conversion. During the treatment period, women must follow the doctor’s instructions, make reasonable adjustments to their diet, improve their health and relaxation, and speed up the time to turn positive. Finally, for the treatment of closed antibody, we should know that turning positive is a persistent process, follow the doctor’s advice during the treatment, reasonable adjustment of lifestyle habits, in order to ensure faster turn positive.