Whether patients with facial allergies can wear masks depends on the material of the mask and the allergen of the individual’s skin, and cannot be generalized. Patients who are allergic to the material of the mask are not recommended to wear the mask, while patients who are not allergic to the material of the mask and are mainly allergic to substances in the outside air can wear the mask, but they should be careful not to wear it for too long. First of all, the material of the mask can be an allergen if the patient is not tested for allergens. When the patient’s facial skin is exposed to this allergen, a delayed hypersensitivity reaction can occur, i.e., the onset of the disease is not immediate after the initial exposure, but requires a latent period of 4-20 days to sensitize the organism, and the patient can have an allergic reaction within 12-72 hours after being exposed to the allergen again, aggravating the facial allergy. Secondly, there are many causes of skin allergy on the face of patients, which are divided into exogenous allergy and endogenous allergy. Exogenous allergies are commonly caused by pollen, dust, mites, skin care products, cosmetics and other allergies; while endogenous allergies are mainly caused by the destruction of skin barrier function or metabolic abnormalities, so some patients with exogenous allergies can wear masks to stop the allergenic substances in the outside air and can wear them if they are not allergic to the mask material. However, patients with other types of allergies can wear masks while their faces are in a more confined space and can produce water vapor when they breathe. Long-term wearing of masks can make the skin of the face in a more humid state, so it is easy to cause bacterial infections that can aggravate facial allergies. At the same time, patients who wear masks for a long time may rub the affected skin repeatedly, which will further worsen the face allergy.