Pediatric itchy rash mostly develops in early childhood, often after papular urticaria or urticaria, initially as a puffy or puffy papule, and after the rash slowly fades, normal skin-colored or light red papules begin to appear, like green beans or broad beans in size, hard to the touch, forming small nodules of itchy rash, and sometimes blisters may appear. Itchy rash in children mainly occurs on the extensor side of the limbs, especially on the lower legs and shin front, but also on the stomach and buttocks, and in more severe cases can develop all over the body. Pediatric itchy rash rarely involves the metacarpophalangeal and bony fossa areas. The exact pathogenesis of pediatric itchy rash is being studied and may be related to individual genetic allergies, often with several cases occurring simultaneously in a single family, and other relationships with allergic reactions, autoimmune and psychiatric factors need to be further confirmed. Some studies have shown that self-conditions, social environment and poor nutrition can also contribute to the development of this disease.