Urticaria has the potential to cause scrotal itching. Urticaria, also known as rubella block, is a limited edema of the skin mucosa due to a temporary increase in vascular permeability, the whole body skin can develop, so it is possible to cause itching in the scrotum area. Most patients can not find the exact cause, common causes are eating or contact with certain allergens, chronic infections, external physical stimuli. It is recommended that patients with itchy scrotum due to urticaria go to regular hospitals and take appropriate medication as prescribed by the doctor, such as loratadine, etc. Prednisone, dexamethasone and other glucocorticosteroid medications should be used under the guidance of the doctor if necessary.