1. Anticholinergics:For patients with prominent tremor and younger age. ①Antan (benztropine hydrochloride), 1-2mg each time, three times a day orally. ②Benztropine (benztropine metavanadate, Cogentin). ③Kaimajun, 2.5mg per dose, orally three times daily. Side effects: dry mouth, blurred vision, constipation, urinary retention, etc. Contraindicated in glaucoma and prostatic hypertrophy. Long-term use may affect memory function. 2. Amantadine: 100mg per dose, orally 2-3 times daily. Use with caution in patients with epilepsy. It can cause insomnia, so it should not be taken at night, but in the morning and afternoon. 3, levodopa (L-dopa): This product is currently the most effective drug for the treatment of Parkinson’s disease, with an efficiency of 75% or higher. Generally start with small dose, gradually increase the dose, and then change to maintenance dose after the effect. The initial dose is 125 mg per tablet, 1 to 2 tablets per time, taken orally 3 to 4 times a day; the dose can be increased to 250 mg per tablet, 1 tablet per time, taken orally 3 to 4 times a day, and generally not more than 5 tablets per day. The most appropriate amount of this product varies from person to person. Each tablet contains 250 mg of levodopa and 25 mg of carbidopa. Start with 1/2 tablet each time and take it orally 3-4 times a day, then add 1/2 tablet each time until 6-8 tablets a day and take it orally in 3-4 times for 20-40 weeks. Each tablet contains 50 mg of carbidopa and 200 mg of levodopa. 4, dopamine agonists: combined with levodopa, can reduce the dosage of levodopa, reduce its side effects, and can greatly improve the efficacy. Side effects include nausea and vomiting. ②Bromocriptine, start with 0.625mg per day, increase 0.625mg every 3-5 days, up to 7.5-15mg per day, divided into 3 doses. ③Praxol, 0.125mg per dose, 3 times daily, gradually increase to 1.0mg, 3 times daily. It has an improving effect on early patients and can also reduce the depressive symptoms in Parkinson’s patients. Combining with levodopa can reduce the dose and side effects of the latter. 5, B-type monoamine oxidase inhibitors: such as Midodopy (Slegiline), 2.5mg-5mg each time, twice a day. Use with caution in psychiatric patients and not in combination with fluoxetine. 6. Catechol-oxo-methyltransferase inhibitor (COMTI): It is ineffective when used alone and can be used in combination with methyldopa to enhance the efficacy and reduce the fluctuation of symptoms. (1) Tolcapone (A is for beauty) 100-200mg each time, 3 times a day. ②Entocapone (Kodan), 200mg each time, 5 times a day.