Complete or incomplete spinal cord injury caused by high-energy trauma such as fall from height, car accident, diving, etc. brings great difficulties to the prognosis of patients. spinal cord injury above T5-6 segment often results in muscle spasm and autonomic dysfunction during the rehabilitation process. The current treatment for muscle spasm is mainly medication, rehabilitation training, etc. Baclofen, tizanidine, botulinum toxin, etc. can be used. The most common drug is baclofen. Patients are advised to read the instructions for use and pay attention to common adverse reactions during the process of use, and can also consult with the clinic for dose adjustment. Autonomic dysfunction such as intractable hypertension can be treated with nitrates.