In order to save the time of the patients, the first-time patients are recommended to do the examination on an empty stomach; for follow-up patients, please bring enough information as follows: 1, blood (fasting): blood routine, liver function, kidney function, lipid analysis, blood glucose, homocysteine, renin + angiotensin + aldosterone; combined with diabetes mellitus is recommended to add 2 hours after meal blood glucose and glycated hemoglobin. 2, urine: routine, urine microglobulin + albumin. 3.Electrocardiogram. 4, Hepatobiliary, pancreatic, spleen and kidney ultrasound, adrenal and renal artery ultrasound, cardiac ultrasound; bilateral common carotid, internal carotid and vertebral artery ultrasound; bilateral subclavian artery ultrasound if necessary. 5. Vascular elasticity monitoring, 24-hour ambulatory blood pressure monitoring if necessary.