During pregnancy, under the influence of hormones in pregnant women, the bones and ligaments of the whole body, especially the pelvis and uterine supporting tissues, become softer, the bones and joints are slightly looser, and mobility increases. The uterine ligaments become enlarged and thickened, and their direction of travel and anatomical position change significantly with the growth of the uterine body. The sacroiliac joint and pubic symphysis become lax and there is mild extensibility. There is also a little mobility of the sacrococcygeal joints to facilitate labor. Excessive laxity of the pelvic joints can cause pain in the area of the bony joints and pubic symphysis, and in severe cases, separation of the pubic symphysis can occur, and pregnant women experience severe pubic symphysis pain and limited mobility. Due to the enlargement of the uterus forward and the anterior convexity of the spine, certain muscle groups are overloaded, especially the dorsal extensors, and the low back and sacral pain is felt in late pregnancy. Due to the forward flexion of the neck and the drooping of the scapula, the ulnar and median nerves are stretched causing pain and numbness in the upper limbs as well as weakness. If there is calcium deficiency in late pregnancy, the fetus can absorb the calcium stored in the osteoclastin in the long bones to replenish, and thus bone pain and bone softening will occur. Therefore, the mother-to-be needs to understand the above knowledge, face these problems correctly, avoid indiscriminate use of medication, moderate activity, more sunshine to increase the absorption of change, and need reasonable calcium supplementation in the middle and late pregnancy under the guidance of a doctor.