Factors in the development of coronary heart disease

  Investigation of the factors triggering coronary heart disease, mainly with the following factors are closely related.  1, age: the disease is mostly seen in middle-aged and elderly people over 40 years old, and progresses faster after 40 years old.  2, gender: the disease is more common in men, the ratio of men to women is 2:1, women suffer from the disease after menopause, when the body estrogen decreased, the blood high-density lipoprotein (HDL) also decreased.  3, occupation: personnel physical activity less, brain activity, often have a sense of urgency workers are more prone to disease.  4, diet: often eat a high-calorie diet, such as more animal fat, cholesterol, sugar and salt susceptible to the disease.  5, blood pressure: increased blood pressure is closely related to the disease. About 60-70% of patients with coronary atherosclerosis have hypertension. And hypertensive patients suffering from this disease is four times higher than those with normal blood pressure. Systolic blood pressure and diastolic blood pressure increase is equally important.  6, lipids: due to excessive fat intake or metabolic disorders resulting in dyslipidemia, such as total cholesterol, triglycerides, low-density lipoprotein (1-DL) or very low-density lipoprotein (VLDL) increased, high-density lipoprotein (HDL), especially its subcomponent II (HDL II) is reduced, are susceptible to this disease, apolipoprotein A (apoA) decreased and apolipoprotein B (apoB) increased is also associated with The disease is also associated with the disease.  7, smoking: smokers compared with non-smokers, the incidence of the disease and death rate increased by 2-6 times, and is proportional to the number of cigarettes smoked per day.  8, excessive alcohol consumption: long-term excessive intake of alcohol can increase the heart rate and blood pressure, causing arrhythmia or myocardial damage, in addition to alcohol contains high calories, can lead to obesity.  9, heredity: autosomal dominant genetic cause of familial hyperlipidemia is these family members susceptible to this disease factors.  10, obesity: over the standard weight of obese people (10% overweight for mild, 20% for moderate, 30% for severe) susceptible to bong disease, rapid weight gain is particularly susceptible to this disease.  11, diabetes: the incidence of diabetes patients is 2 times higher than that of people without diabetes.  12, other factors: trace elements such as chromium, manganese, bell, vanadium, selenium intake decreased, aluminum, cadmium, cobalt intake increased; type A personality (impatient, aggressive and competitive, focused on work and rest is not grasping, forcing themselves to strive for achievement); the presence of hypoxia, vitamin C deficiency, arterial wall enzyme activity is reduced and other factors that can increase vascular permeability are susceptible to this disease. Excessive coffee consumption can also increase cholesterol, and contraceptive drugs can promote blood clotting and lead to heart disease.  Among the above factors, hypertension, hyperlipidemia, diabetes, obesity, smoking and excessive alcohol consumption are the predisposing factors.