Hypogonadism is commonly associated with premature ejaculation and erectile dysfunction, and the medications used for different diseases are different, with common therapeutic drugs such as selective 5-hydroxytryptamine reuptake inhibitors, phosphodiesterase 5 inhibitors, and so on. It is best to follow the doctor’s instructions and choose the individualized treatment medication that suits the patient. 1. Premature ejaculation: patients with premature ejaculation can use selective 5-hydroxytryptamine reuptake inhibitors under the guidance of a doctor, and common drugs include dapoxetine, sertraline, fluoxetine, etc. Dizziness, headache, vomiting, nausea, and other symptoms may occur after the use of drugs. 2. Erectile dysfunction: impotence patients can follow the doctor’s instructions to use phosphodiesterase 5 inhibitors for treatment, commonly used drugs such as sildenafil, etc., after the use of the drug may appear indigestion, headache, facial flushing and other adverse reactions. Specific treatments also need to go to the hospital to check the diagnosis, under the guidance of the doctor to choose, the patient must not unauthorized use of drugs, stop or change drugs.