Hypogonadism after the age of 40 is considered to be a decline in hormone levels, inflammation of the reproductive system, mental stress, the presence of underlying diseases, etc. It is important to choose the right medication according to the specific cause of the disease. Including estrogen, antibiotics and so on. 1. Decrease in hormone level: After 40 years of age, estrogen level gradually decreases, which will cause hypogonadism, and can be supplemented with estrogenic drugs, such as testosterone undecanoate capsule and methyltestosterone tablets under the guidance of a doctor. 2. Inflammation of the reproductive system: If men have some inflammation of the reproductive system, such as prostatitis, etc. can also lead to ejaculatory pain and other effects on sexual function, you need to use antibiotic drugs to control the infection, such as amoxicillin, levofloxacin and so on. 3. Mental stress: prolonged mental stress and mental tension can also affect the sexual function, this situation does not need to be treated with medication, to regulate from the usual life, should learn to release the pressure, go outdoors more to do sports. 4. the existence of underlying diseases: if men after the age of 40 there are some underlying diseases, such as hypertension, diabetes, etc., will also affect the sexual function, these diseases will affect the penile area of the congestion, resulting in sexual dysfunction, the need for medication to control blood pressure (nifedipine, etc.), blood glucose (metformin, etc.), and so on. After 40 years of age, hypogonadism, should be timely consultation, clear cause symptomatic treatment, the above drugs should be used under the guidance of a doctor, do not blindly use their own.