Arterial thrombosis in the calf occurs mostly in elderly patients with atherosclerosis or trauma leading to the appearance of arterial thrombosis in the calf. The best treatment is to have the opportunity to dissolve the thrombus and recanalize the artery through medication within 2-6 hours of the formation of the thrombus. The shorter the time, the greater the chance of recanalization. The purpose of thrombolysis can be achieved by intravenous infusion of the drugs rTPA and urokinase in a short period of time. In addition, if arterial thrombosis is formed in the lower leg for a longer period of time, surgical intervention is required. The most common surgical procedures include lower limb vascular thrombectomy, which completely pulls out the formed arterial thrombus and reopens the vessel. Stenting can also be performed at the obvious location of the thrombus to dilate the blocked blood vessel and allow blood flow through the artery to ensure blood supply. In addition to these options, oral anticoagulant drugs such as aspirin, lipid-lowering drugs such as Rosuvastatin calcium, and blood clotting herbs should be taken to regulate the treatment. Through a comprehensive treatment plan, the arterial thrombosis of the calf can be completely cured.